flag ha tagged bap1 variant plasmids Search Results


bap1 loss  (TargetMol)
93
TargetMol bap1 loss
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Bap1 Loss, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bap1  (Sino Biological)
94
Sino Biological bap1
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Bap1, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plvx hygro  (Addgene inc)
93
Addgene inc plvx hygro
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Plvx Hygro, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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acknowledgements 447 flag ha bap1 plasmid  (Addgene inc)
90
Addgene inc acknowledgements 447 flag ha bap1 plasmid
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Acknowledgements 447 Flag Ha Bap1 Plasmid, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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expression plasmids for flag-ha-bap1  (Blue Heron Biotech)
90
Blue Heron Biotech expression plasmids for flag-ha-bap1
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Expression Plasmids For Flag Ha Bap1, supplied by Blue Heron Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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expression plasmids for flag-ha-bap1 - by Bioz Stars, 2026-05
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bap-1  (Bio SB Inc)
90
Bio SB Inc bap-1
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Bap 1, supplied by Bio SB Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bap 1  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc bap 1
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Bap 1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1 ap  (Proteintech)
93
Proteintech 1 ap
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
1 Ap, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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locus type entrez nucleotide attrs text nm 004742 term id 66346707  (OriGene)
90
OriGene locus type entrez nucleotide attrs text nm 004742 term id 66346707
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Locus Type Entrez Nucleotide Attrs Text Nm 004742 Term Id 66346707, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bap 1  (Santa Cruz Biotechnology)
96
Santa Cruz Biotechnology bap 1
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Bap 1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti-bap  (GenScript corporation)
90
GenScript corporation anti-bap
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
Anti Bap, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse anti-bap  (GenScript corporation)
90
GenScript corporation mouse anti-bap
A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of <t>BAP1</t> mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.
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Image Search Results


A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of BAP1 mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.

Journal: Cell Death & Disease

Article Title: Identification of targetable epigenetic vulnerabilities for uveal melanoma

doi: 10.1038/s41419-025-08295-4

Figure Lengend Snippet: A Mean viability of the three UM cell lines following 72 h treatment with 932 epigenetic modulators at a concentration of 1 μM ( n = 2) relative to the negative control (0.1% DMSO treatment). Hit cut-offs (dashed lines) were determined as the mean percentage viability of the negative controls in each cell line minus three standard deviations. Yellow dashed line is the hit cut-off for MP41 cells (65.8% viability), purple dashed line is the hit cut-off for MP46 cells (74.0% viability), and the green dashed line is the hit cut-off for MP38 cells (58.9% viability). For full list of compounds and average UM cell viabilities, see Supplementary Data . B Radar plot showing the mean difference in percent of cell viability of UM cells caused by 72 h 1 μM treatment with 932 compounds, relative to the DMSO control. Negative values, shown in gray, indicate ineffective compounds leading to greater cell viability than the negative control. The positive values, shown in color, indicate compounds that induced cell death, with higher peaks indicating greater cell death. Compounds are grouped by drug mechanism of action. C Pie charts of the molecular activities of all screened compounds ( n = 932) (left) and the hits identified ( n = 24) (right). D Concentration-response experiments for the 24 hit compounds (10 concentrations, n = 4 per concentration per cell line). Center values represent mean viability, error bars represent standard error of mean (SEM). E Log IC 50 (M) values of the top hit compounds for each cell line. Error bars represent 95% confidence interval. F Log IC 50 (M) of BAP1 mutant cell lines (MP46 and MP38) plotted against the log IC 50 (M) of the BAP1 wildtype cell line (MP41) for each drug treatment.

Article Snippet: Given the global epigenetic changes elicited by BAP1 loss, we performed a comprehensive epigenetic compound screen on UM cells, using a well-characterized drug library consisting of 932 cell-permeable, small-molecule modulators (TargetMol, L1200, July 2022; Supplementary Data ).

Techniques: Concentration Assay, Negative Control, Control, Mutagenesis